• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
  • 法律状态
  • 优先权
    • 专利摘要:
    The invention relates to a hypodermic syringe head (21) for an injection syringe (20) with a needle unit (12) arranged in a guide sleeve (5) and a pinion (2) through which the needle unit (12) is axially displaceable relative to a syringe barrel (12). 15) is movable from a rest position to an activation position. The drive pinion (2) has at least one guide nub (1) which can optionally be set into engagement with one of two slide tracks (10) provided in the guide sleeve (5), the slide tracks (10) having oppositely directed slopes. Furthermore, the invention also relates to a squeezing unit (25) and an injection syringe (20) with a syringe cylinder (15), the injection syringe head (21) and the squeezing unit (25).
    公开号:AT511259A2
    申请号:T680/2011
    申请日:2011-05-12
    公开日:2012-10-15
    发明作者:
    申请人:Pharma Consult Gmbh & Co Nfg Kg；
    IPC主号:
    专利说明:

    14:39:40 12-05-2011 5/38 25 • ·
    -1 -
    The invention relates to a hypodermic syringe head for a hypodermic syringe with a arranged in a Führungshüise and slidable therein needle unit and a pinion through which the needle unit is axially movable relative to a syringe barrel from a rest position to a Aktrvierungsstellung.
    In the present specification, the directions "proximal * and" distal * are defined as viewed from the side of the patient. Thus, the proximal side is always facing the patient in the components described below and the distal side always averted from this injection syringes, especially disposable syringes, are known means for administering drugs. In disposable syringes, which are often used by the patient himself, the cannula is connected to the syringe barrel just prior to application by a rotary motion.
    From AT 404 430 B a syringe head is known in which the cannula pierces either by a left or right rotation of a sealing disc at the outlet of the syringe barrel so that the patient previously requires no guidance in which direction to turn, or whether a direction of rotation A safe use of the syringe is contrary According to the teaching of AT 404 430 B, a cannula holder is inserted into a cannula carrier guide, wherein the cannula carrier has a branching to the proximal end, Y-shaped guide groove into which a guide pin engages in the cannula carrier guide When turning the Cannula carrier passes through the guide pin either the left or the right leg of the groove, causing the Kenfilenträger moves in a right or left rotation in the direction of sealing disc The disadvantage of this solution is that the guide pin angeor on the inside of the cannula carrier guide dnet must be, which is complex in production and associated with high reject rates. A further disadvantage is that it is still possible to lead the cannula holder out of the end position, ie the user intentionally or unintentionally connects the cannula and the needle N2011 / 14400 12/05/2011 14:41
    No. ; R374 P.005 / 038 14:40:19 12-05-2011 6/38 25 • * • · · * · · »· ·
    * * II -2-pronged washer can loosen again. Furthermore, it is disadvantageous that the sharpened distal end of the cannula rotates into the sealing disc and can generate abrasion particles from the material of the sealing disc during insertion, which then pass into the liquid medicament. Furthermore, the used cannula can be protected again after use only by reapplying a part of the protective cap, which can be associated with stitches.
    From US 5 250 037 A and DE ΘΘ3 19 702 T2 discloses a syringe head of the type mentioned in the introduction, in which a pinion unit connects a needle unit before injection with the syringe barrel. The disadvantage here is that the pinion is at the same time the protective cap of the syringe and is removed after the operation of her. As a result, the Nadeieinheit remains loosely and unattached connected to the syringe barrel during the tnjektionsvorganges. Again, the used cannula can be protected after use only by re-putting the Schulzkappe again, which may be associated with puncture injuries.
    Another injection syringe has become known from WO 2009/097634 A1. In this case, this hypodermic syringe comprises a syringe head covered by a protective cap in the initial state, which in turn has a cannula held in a cannula holder, a guide sleeve receiving the cannula holder together with the cannula and a drive part for the adjustment of the cannula together with the cannula holder. At the end facing the syringe barrel, a sealing insert is snapped onto the guide sleeve. To implement the rotational movement starting from the cap tip on the drive part and subsequently on the needle holder of the drive part is provided on its outer side with a slide track which cooperates with a guide pin on the inside of the Fqhrungshülse Again, there is the disadvantage that the guide pin is arranged on the inside of the guide sleeve, which is complex in the production and associated with high reject rates. Likewise, however, there is also no clear end position positioning of the can with its needle holder in the activated position, in which the cannula extends through the bottom of the sealing insert. Furthermore, an unintentional displacement of the coupling side can take place with respect to the piston stopper, as a result of which the tightness and above all the sterility are no longer guaranteed.
    The present invention aims to provide a hypodermic syringe head and a squeezing unit of the kind set forth in the opening paragraph, which obviates these disadvantages. N2011 / 14400 12/05/2011 14:42
    No .: R374 P.006 / 038 14:41:04 12-05-2011 7/38 25
    -3- avoids, and in particular after connection of the cannula with the syringe cylinder prevents further mobility of the cannula. Another object of the invention is to connect the cannula with the syringe barrel so that no abrasive particles can be generated. Furthermore, an improved coupling connection between the piston plug and the coupling part of the ejection unit should also be created.
    The injection syringe head according to the invention achieves this by virtue of the fact that the pinion has at least one guide nub which can be selectively set into engagement with one of two slide tracks provided in the guide sleeve, the slide tracks having opposite inclinations.
    It is advantageous that the formation of the Führungsnoppens can be done technically easier and especially the safety of the function of the entire syringe can be increased. Furthermore, the formation of the slide tracks is also easier and above all safer in the application.
    A further embodiment provides that the drive pinion comprises two guide knobs, which are arranged in a perpendicular to a longitudinal axis aligned plane and in the circumferential direction distanced from each other and the displacement of the needle unit from the rest position to the activation position only one of the two guide knobs with one of Thus, the reliability is additionally increased and created an even better operation opportunity.
    A further preferred embodiment has the features that in the FŸhrungshülse in a peripheral region between the two cam tracks an exemption is formed and the exemption for receiving that Führungsnoppens serves, which is engaged during the adjustment of the needle unit with none of the Kuißenbahnen. Thus, despite the two guide knobs, on the one hand, an exact guidance of one of the two knobs can be created and, on the other hand, jamming during the rotary movement can be prevented.
    Another embodiment is characterized in that the needle unit, in particular its Kanüienhaiter, and the FührungshOlse are held in the activated position by means of cooperating locking elements of a Arretiervomchtung in the axial direction relative to each other. Thus, before, during and after delivery of the drug always a secure position of the cannula is achieved, and an unwanted Axiaiveriage-omg avoided. 12/05/2011 14:42
    No .: R374 P.007 / 038 25 14:41:46 12-05-2011 8/38 -4-
    A further embodiment provides that the needle unit, in particular its cannula holder, is rotatably coupled to the pinion about the longitudinal axis but locked in the axial direction. Thus, a pre-assembly of the canoe together with the needle holder in Triebling done without the necessary freedom of movement of rotation is limited.
    A further preferred embodiment has the features that the needle unit, in particular the cannula holder, is mounted in the guide sleeve in a straight line in the axial direction. This achieves a pure puncture movement in the region of the sealing element and avoids the leaching of particles from the sealing element. Thus, an even safer delivery of the drug is achieved in terms of purity.
    Another embodiment is characterized in that at the end of each slide track a link extension is provided, in which the guide knobs can be latched. In the presence of an additional residual hook can also be formed latched in the Ku-lissenerweitemng.
    A further preferred embodiment is characterized in that the distal end of the guide sleeve is designed as a coupling. Alternatively, the distal end of the guide sleeve may be formed flat.
    A further embodiment provides that at least one longitudinal rib is arranged on an outer side of the guide sleeve, which is rotationally fixedly supported on a locking member of a protective cap receiving the injection syringe head. This prevents twisting of the guide sleeve during the activation process
    The invention also relates to a squeezing unit for a hypodermic syringe comprising a piston rod, a coupling part with a base body and a protruding on the side facing away from the piston rod Kupplungsförtsatz and a piston plug with an end facing away from one of the piston rod end extending into the blind hole, which with a Closed bottom, wherein the coupling extension protrudes into the blind hole and is arranged in an unactuated Ausgansstellung the piston plunger in the axial direction of the base body and further the bottom of the blind hole is un-pierced by a coupling end of the coupling extension attachment. N2011 / 14400 17/05/2011 14:43
    No .: R374 P.008 / 038 25
    -5-
    14:42:27 12-05-2011 9/38
    In this case, the object of the invention is thereby independently gpiftst that Kuppiung «. Furthermore, at least a first locking element is arranged, which is inserted in the unactuated Ausgansstellung in a arranged in the piston stopper in the region of the blind hole recess. The advantages resulting from the combination of features of this claim are that such a pre-assembly and above all a safe insertion of the piston plug can be done in the syringe zyfinder. This axially acting support can be overcome for squeezing the drug and also serves during transport and storage to ensure that the piston stopper remains intact in the region of its blind hole. This avoids unwanted displacement even when shaken.
    Another embodiment is characterized in that the first latching element abuts in abutting position of the base body and the piston plug at the bottom of the blind hole in the region penetrated by the coupling extension. As a result, a supporting effect of the pierced soil is achieved and so the tightness even when squeezing the drug in this section made sure.
    A further embodiment provides that on the coupling extension between the base body and the first locking element, a further locking element is arranged, which is supported in the return movement of the squeezing unit to a formed in the blind hole of the Koibenstopfens shoulder fitting Thus, the RücksteHbewegung is facilitated and pulled a stiffening of the far Injection syringe head prevented.
    Another embodiment is characterized in that the Kupplungsförtsatzen-de is formed on the side facing away from the piston rod arrow-shaped tapered and at least one, preferably two, the cross section of the coupling extension superior latching arms. Thus, the penetration force is reduced for the coupling movement and beyond also the retention force increased by the formation of a more stable Schütter in the sealing element. Furthermore, a better anchoring effect or a decay of the one or more locking arms can be achieved by the partially penetrating into the elastic material of the sealing element, especially when coated with a lubricant seal element.
    A further embodiment provides that the base body of the coupling part on the side facing the piston rod comprises elastically deformable coupling arms, which are releasably coupled with a coupling element ausgebtldeten on the piston rod. There · N2011 / 14400 17/05/2011 14:44
    No .: R374 P.009 / 038 25 14:43:11 12-05-2011 10/38 -6-with the uncoupling of the piston rod can be easily done after the return movement of the entire needle unit.
    A further preferred embodiment is characterized in that the squeezing unit further comprises a handling element which can be coupled to a distal end of a syringe barrel, and a clear inner width of a passageway in the handling element is made larger in a distal section than an outer cross-sectional dimension of the coupling arms their undeformed position. Thus, the Spritzenzyiinder can be easily formed with a nearly same inner dimension over the greppten part of its length. As a result, mold costs and inaccuracies in the production of the Spritzenzyf are avoided. By additionally engageable handling element, the reliability can be increased and above all the reuse can be prevented by simple auszubikiende components.
    Another embodiment is characterized in that between the base body of the coupling part and the handling element a holding device is designed with cooperating adhesive elements, which prevent at least one axial adjustment of the coupling part in the proximal direction in engaging holding elements. In particular, unintentional reuse and the possible transmission of diseases can be prevented.
    A further embodiment provides that at least one guide element is arranged on the handling element in the region of its distal end, which protrudes into the cross section of the passage channel. Thus, even after uncoupling the piston rod from the coupling part with the protected needle unit reinsertion and reuse prevented.
    The invention also relates to a syringe with a syringe barrel, a syringe head and a squeezing unit of the above-described training. For a compact and above all safe and easy-to-use hypodermic syringe is created, which can be applied by medically unformulated persons and thereby aulweist a high level of reliability.
    The invention will be explained in more detail with reference to embodiments shown in the drawings.
    In each case, in a highly schematically simplified representation: N2011 / 14400 12/05/2011 14:44
    No .: R374 P.010 / 038 25 14:43:53 12-05-2011 11/38 et * «« * * * * * * «« · · • · * · »** ·« «» »4 FIG. 1 is an exploded view of the syringe head; FIG. Fig. 2 is an exploded view of the InjekÜonaepritzonkopfes rotated 160 "axially; Fig. 3 is a syringe head rotated 90 ° axially; Fig. 4 is an exploded view of a syringe in an alternative embodiment; 5 shows a section through the syringe head of an alternative embodiment; 6 shows a further possible embodiment of a syringe in unopened original position, cut in view; FIG. 7 shows the injection syringe head of the injection syringe after activation of the injection syringe according to FIG. 6, cut away in a view; FIG. FIG. 8 shows the injection unit of the injection syringe after activation of the injection syringe according to FIG. 6, cut away in elevation; FIG. 9 shows the disposal position of the injection syringe according to FIGS. 6 to 8, cut in view; 10 shows the ejection unit and the syringe barrel with handling element according to FIGS. 6 to 9 in an exploded view, in a sectional view; 11 shows the injection syringe head and the protective cap according to FIGS. 6 to 9 in an exploded view, in a sectional view; Fig. 12, the guide sleeve of the injection syringe head according to the Rg. 6 to 11, in perspective view.
    By way of introduction, it should be noted that in the differently described Ausführungsfbr-men the same parts are denoted by the same reference numerals or identical component names, the disclosures contained in the entire description can be mutatis mutandis to the same parts with the same reference numerals or identical component names. Also, the location information chosen in the description, such as N2011 / 14400 1 / 05 / 201Ί 14:45
    No .: R374 P.011 / 038 25 14.44: 27 12-05-2011 12/38 • »> -8-Asked figure and are in a position change mutatis mutandis to transfer to the new location.
    According to FIG. 1, a hypodermic syringe head 21 has a needle unit 12 with a cannula 3 and a cannula holder 4. The needle unit 12 is inserted into a guide sleeve 5. The drive of the Nadeieinheit 12 in the direction of a syringe cylinder, not shown, to connect the cannula 3 immediately before the injection with the sealed syringe barrel, carried by a pinion 2, soft on the Nadeieinheit 12 inserted wind. The pinion 2, the needle holder 4 and the Fühmngshülse 5 are preferably made of plastic.
    In Fig. 3 of the finished mated injection syringe head 21 is shown. The pinion 2 has two guide knobs 1, which are arranged in the unactuated state of the injection syringe zκυμιββ z i before the entrance of each lunissenbahn 10. The slide tracks 10 are recesses in the Führungshüfee 5. They run on the guide sleeve 5 with each opposite pitch. If the pinion 2 is brought into a rotational movement, which can take place, for example, that lamellae of a protective cap, not shown in FIGS. 1 to 3, engage webs 13 of the pinion 2 extending along a longitudinal axis 19, a guide nub 1 becomes one of the cam tracks 10 guided, while the other guide nubs 1 freely enters into a free space or an exemption 18 of the guide sleeve 5. The guide nubs 1, which is guided in a slide track 10, follows the slope of this slide track 10 and moves the pinion 2 together with the needle unit 12 in the direction of the syringe barrel. In this way, the needle unit 12 is moved toward the syringe barrel both in a left turn and in a right turn. The circumference of the needle unit 12 and the correspondingly shaped inner channel of the guide sleeve 5 are formed so that the needle unit 12 can not rotate when driven by the pinion 2, but is linearly moved towards the syringe barrel. According to FIGS. 1 to 3, the rotation of the pinion 2 for complete movement of the needle unit 12 takes place by about 90e.
    The pinion 2 has further shown in FIG. 2, a latching hook 8, which is arranged approximately at the height of the guide knobs 1 on the other peripheral side of the pinion 2. In the unactuated state of the injection syringe head 21, the latching hook 8 is positioned in a window 9 of the guide sleeve 5. To bring the latching hook 8 out of this position requires overcoming a mechanical resistance, whereby the injection N2011 / 14400 12/05/2011 14:46
    No .: R374 P.012 / 038 14:45:11 12-05-2011 13/38 25 · ι · «» »» »» # # # # # #. I * * «< In its unactuated state, the syringe head 21 is secured against unintentional actuation. Upon rotation of the pinion 2 of the latching hook 8 moves to the end of that slide track 10, which is not occupied by a Fuhr nubs 1. The link tracks 10 each have, according to FIG. 3, a horizontal link extension 11.
    After completion of the shoot rotation are located in a gate extension 11 Fihrungnoppen 1 and in the other setting extension 11 of the locking hooks 8. Unscrewing the pinion 2 and thus further movement of the needle unit 12 is no longer possible because the opposing slopes of the slide tracks 10 the Blocks movement of the spring stop 1 and the latching hook 8 to each other. This favors the safe handling of the syringe, since a repeated connection and detachment of the cannula of the syringe barrel is impossible.
    In a first embodiment according to FIGS. 1 to 3, the injection syringe head 21 has at its distal end a coupling 6 which is preferably designed as a distal end of the guide sleeve 5. The coupling 6 can be assembled, for example, with a sealing element 7 of the syringe barrel in the form of a plug connection. The distal end of the sealing member 7 may be fixedly connected to the syringe barrel or may be part of a retractable assembly in the syringe cycler after injection.
    As a result, the injection syringe head 21 can be attached to a plurality of injection syringe types.
    Fig. 4 shows a complete syringe 20 according to the invention in a second embodiment. The distal end of the guide sleeve 5 is flat and connects to a sealing washer 19. In the assembled state, the sealing disc 19 rests on the proximal end of a syringe cylinder 15, in which a piston rod 17 and a piston stopper 16 are inserted for moving the liquid. The syringe head of the syringe barrel 15 together with the injection syringe head 21 are covered by a protective cap 14.
    According to FIG. 5, the protective cap 14 is attached to the syringe barrel 15 and thereby presses the guide sleeve 5 onto the sealing disc 19 and the proximal end of the syringe barrel 15. The protective cap 14 comprises in a known manner a protective cap base 22 and a protective cap tip 23, which pass over a magnetic breaking point 24 are connected. By turning the cap tip 23, the predetermined breaking point 24 between this and the protective cap base 23 is broken. Inner fins of the cap tip 23 engage in the webs 13 of the pinion 2 and thus also put him in a rotary motion. Thus, finally, the pinion 2 and the needle unit 12 in the above N2011 / 14400 12/05/2011 14:47
    No .: R374 P.013 / 038 25 14: 45: 5¾ .12-05-2011 25 14/38
    10 described manner moved in the direction of the Spritzenzyünders 15 and the sealing washer 19 pierced.
    Regardless, it would also be possible to find Auslangen with only a single Führungsnoppe 1 on pinion 2 and this guide knob 1 either in one of the two oppositely-formed link tracks 10 depending on the selected direction of rotation (clockwise or counterclockwise) into engagement and thus effect the associated adjustment of the cannula holder 4 together with the cannula 3 in the direction of the syringe barrel 15. Furthermore, even the arrangement or the provision of the latching hook 8 in conjunction with the window 9 could even be dispensed with, as a result of which simpler forms can be achieved.
    FIGS. 6 to 12 show a further embodiment of an injection syringe 20, which may be independent of itself, wherein the same reference numerals or component designations are used again for the same parts as in the preceding FIGS. 1 to 5. To avoid unnecessary repetition, reference is made to the detailed description in the preceding Figs. 1 to 5 or reference.
    This further embodiment of the injection syringe 20 shown here, in particular its injection syringe head 21, is similar to that of the injection syringe head 21 which has been described in FIGS. 1 to 3.
    Thus, the syringe 20 comprises the syringe barrel 15 for receiving the drug to be dispensed, in which at its proximal end of the injection syringe head 21 and in its distal end, a squeezing unit 25 is arranged. The injection syringe head 21 is in turn covered by the protective cap 14 and thus protects the projecting in the rest position or initial position proximal tip of the cannula 3 from contamination and unwanted stitch injuries. The protective cap 14 with its protective cap base 22 is plugged or snapped onto the proximal end of the syringe barrel 15 and preferably held against rotation by the radial prestress of the protective cap base 22. By corresponding mutually engaging holding means, the protective cap base 22 is in the axial direction at the proximal end held the syringe barrel 15. Furthermore, between the proximal end of the syringe barrel 15, in particular its end face, and a shoulder of the protective cap base 22 projecting radially in the direction of the longitudinal axis, a sealing ring 60 is preferably arranged. Thus, a bacteria-tight closure is achieved in the transition region of the syringe barrel 15 and the protective cap 14.
    N2011 / 1440Q 12/05/2011 14:47
    No .: R374 P.014 / 038 -11- 25 «· 1f 46: 4¾ * 12-05-2011 15/38
    At the drive finger 2, two guide knobs 1 are arranged in this embodiment shown here, which are arranged spaced apart in a plane oriented perpendicular to the longitudinal axis and in the circumferential direction. These are for displacing the needle unit 12 from the rest position towards the activation position with only one of the two slide tracks 10 into engagement, whereby the activation and the associated axial longitudinal adjustment of the cannula 3 together with the cannula holder 4 out in the direction of the syringe barrel 15 takes place while the Sealing element 7 is pierced in the region of its proximal end of the cannula tip. Thus, a line connection between the interior of the syringe barrel 15 and the cannula 3 is created. The drive of the pinion 2 is effected by appropriate rotational movement of the cap tip 23 about the longitudinal axis. Here, the one or more webs 13 of the pinion 2 with the above-described inner fins of the cap tip 23 are engaged.
    As can now better be seen from a synopsis of FIGS. 6, 7 and 11, in the region of the proximal end of the guide neck 5 that region is provided which forms the two slide tracks 10. These two mutually oppositely oriented slide tracks 10 are offset in the circumferential direction to each other to be brought into engagement with one of the two guide knobs 1 at a corresponding activation. In order to provide sufficient freedom of movement for the further guide nubs 1, which is out of engagement with one of the two slide tracks 10, the release 16 is formed here in a peripheral region between the two slide tracks 10 and serves to receive one of the two guide knobs 1. In the present embodiment the release 18 is formed by a radial enlargement and a concomitant decrease in the wall thickness of the guide sleeve 5. The two slide tracks 10 are thereby formed as preferably slot-shaped recesses or openings in the outer wall of the guide sleeve 5 and thus provide even better guidance of the two guide knobs 1 from. At the end of the slide tracks 10, in turn, the previously described preferably horizontally formed link extension n is formed, is arranged in one of the two guide nubs 1 after appropriate displacement in the activation position.
    In order to achieve a certain relief for the Montagevoigang, it is advantageous if the needle unit 12, in particular the needle holder 4, with the pinion 2 rotatable about the longitudinal axis, but locked in the axial direction is coupled. For this purpose, as best seen in FIG. 11, at least one radially projecting projection 26 on N2011 / 14400 12/05/2011 14:48
    No. ; R374 P.015 / 038 -12-
    Shaft 28 of the KanQlenhalters 4 is arranged, which can be brought into engagement with a preferably radially circumferential recess 27 in the pinion 2. Preferably, the projection 26 may also be formed circumferentially, which engages in a preferably annular groove, which forms the recess 27, for mutual locking.
    However, it would also be possible independently to provide the recess 27 in the shank 28 of the cannula holder 4 and the projection or projections 26 on the pinion 2.
    On the shaft 28 of the needle holder 4, a projection 29 is formed in the region of its distal end, the shaft 28 projecting radially beyond. This preferably ring-shaped projection 29 can with its proximal end at the distal end of the pinion 2 in the locked hzw. held slope to be planted.
    In order to achieve an exact linear axial movement of the cannula 3 during its axial displacement in the guide sleeve 5, the needle unit 12, in particular the cannula holder 4, is correspondingly rectilinearly guided in the guide sleeve 5. For this purpose, for example, at least one guiding element 30 can be arranged at the attachment 29 of the cannula holder 4, which is in the direction of engagement with a guide track, not shown, on the inside of the guide sleeve 5. Preferably, a plurality of guide members 30 may be provided with cooperating FOhmngsbahnen in the guide sleeve 5. Furthermore, the cannula holder 4 can also be coupled locked in the axial direction after insertion into the guide sleeve 5 in the rest or initial position in the direction of the proximal side. Thus, a certain coupling effect is also achieved during the assembly process in addition to the longitudinal guide and prevents unintentional release of the Fühmngshülse 5.
    As previously described, the protective cap base 22 of the protective cap 14 is snapped onto the proximal end of the syringe barrel 15 and held almost rotationally against it by the radial bias thereof. In order to prevent relative displacement of the guide sleeve 5 with respect to the protective cap 14, in particular its protective cap base 22, at least one longitudinal rib 31 is arranged or formed on an outer side of the guide sleeve 5. The section of the guide sleeve 5 is received in a passage opening in the protective cap base 22, with proximal ends of the longitudinal ribs 31 being supported on locking elements 32 provided on the inside of the protective cap 14 accommodating the injection syringe head 21. As a result of the interaction of the preferably several longitudinal ribs 31 with the one or more latching elements N2011 / 14400 in / nc / om 1 1 / in Klr * 0Ί7Δ p mfi / nsa 25 • 12-05-2011 17/38 ♦ Λ * Μ8: Κ >
    The guide sleeve 5 is held locked relative to the protective cap 14 in its rotation about the longitudinal axis.
    Thus, as already described above, the activation of the needle unit 12 by the fact that the cap tip 23 is rotated about the longitudinal axis in one of the two directions - clockwise or counterclockwise - and thereby the predetermined breaking point 24 between the cap tip 23 and the protective cap base 22 is severed. Due to the drive connection of the protective cap tip 23 with the pinion 2 and subsequently the guided adjustment of the pinion 2 with its guide nub 1 in one of the slide tracks 10, the axial displacement of the cannula 3 together with the needle holder 4 in the distal direction towards the syringe cylinder 15th In this case, the needle holder 4 slides in a straight line in the axial direction guided in the guide sleeve 5 towards the sealing element 7 and pierces it.
    If this activation position is reached, the needle unit 12, in particular the cannula holder 4, is axially held or arrested on the guide sleeve 5. This takes place in that on the one hand the projection 29 of the cannula holder 4 forms a first locking element 33 on its proximal side. Another locking element 34 is formed or arranged on the guide sleeve 5 and preferably arranged a radially elastically deformable spring arm. The further locking element 34 engages behind the first locking element 33 in the activation position of the needle unit 12, whereby an axial retention of the loading unit 12 in the proximal direction is achieved. The two locking elements 33, 34 form a locking device 35 in the activation position. The needle unit 12, in particular the projection 29, comes in the activation division at a arranged in the interior of the guide sleeve 5 bottom element 36 to the plant. In the bottom member 36, a passage opening for the passage of the distal end of the cannula 3 is provided. Thus, in the activation position, the needle unit 12 with its attachment 29 is held locked on both sides in the axial direction. On the one hand by the bottom element 36 and on the other hand by the interaction of the locking element 33, 34. By the Arretie-relement 34, a proximal Axialveriagerung the needle holder 4 can be prevented, whereby the delivery of the drug can be carried out with the squeezing unit 25 without unwanted detachment or Distancing the cannula 3 from the syringe 20 takes place.
    From a synopsis of FIGS. 6, 8 and 10, the squeezing unit 25 can be seen in the direction of the distal end of the syringe barrel 15, which in turn forms a piston stop N2011 / 14400
    λ ο i nc onn 1Λ- / 1Π No p ni7 / n3R 25
    16, a piston rod 17 and a coupling part 37 coupling or connecting the piston rod 17 to the piston plug 16 comprises the .DELTA.10 Piston stopper 16, starting from an end facing the piston rod 17, has a blind hole 3Θ extending into it, which is closed by a bottom 39 on the proximal side. The outside of the piston stopper 16 is sealingly, but slidably on the inside of the syringe barrel 15 at.
    The coupling part 37 comprises a base body 40, from which, starting in the direction of the piston stopper 16 - ie in the proximal direction - a protruding clutch extension 41 extends. The clutch extension 41 protrudes into the blind hole 38 with its clutch extension end 42. In the unactuated initial position of the ejection unit 25, the coupling extension end 42 is preferably arranged at a distance from the bottom 39, so that the bottom 39 forms a not pierced membrane which bacteria-tight in the interaction of the piston stopper 16 closes the interior of the syringe barrel 15. Furthermore, in the unactuated initial position of the piston stopper 16 is arranged in the axial direction of the base body 40 distant. For Lagearretierung the piston stopper 16 on the coupling extension 41 may be arranged or formed on the coupling extension 41 at least a first locking element 43 which engages in the unactuated initial position in a arranged in the piston stopper 16 in the blind hole 38 recess 44 and is inserted. In this case, it would also be possible independently to arrange the latching element 43 on the piston stopper 16 and the latching recess 44 on the coupling extension 41 or on it.
    By the interaction of the first latching element 43 with the latching recess 44 takes place an axial mutual support or locking of the piston plug 16 on the coupling extension 41. Thus, in this position, the preassembled Auspresseinheit 25 are inserted into the syringe barrel 15 after filling with the drug to be dispensed. Before filling with the drug nor the unit of the injection syringe head 21 is to be mounted or attached to the syringe barrel 15. Thus, first, the unit of the injection syringe head 21 can be assembled and inserted from the distal end into the syringe barrel 15. In this case, the unit of the injection syringe head 21 may already be sterilized. After insertion in a sterile environment, the drug should be filled. Subsequently, the likewise sterilized squeezing unit 25 is likewise used. Thus, the interior receiving the medicament is sterile up to activation. Only through the activation access to the drug on the cannula 3 is created. N2011 / 14400 1 o i ηκ / "5η 11 1A Nr R374 P.018 / 038 25
    44: 49: ¾ * 12-05-2011 • * * * • »· · II I I · I · I · * 19/38 -15-
    The clutch extension end 42 of the coupling extension 41 is formed on the side facing away from the piston rod 17 side - ie at its proximal end - arrow-shaped tapered. This arrow-shaped taper serves to be able to enter a formed in the sealing element 7 further blind hole and between the Kupplungsfort-set end 42 and the sealing element 7 to provide a coupling connection for the return movement of the entire unit of the Fnjektionsspritzenkopfes 21. In order to form this coupling connection, preferably at least two latching arms 45 projecting beyond the cross-section of the coupling extension 41 are provided on the coupling extension end 42. The one or more locking arms 45 have a certain inherent rigidity and can be inserted by the elastic deformation of the material of the sealing element 7 in the further blind hole. Through this design, the latching arms 45, the insertion of the hitch be-ments end 42 in the fiackfoch of the Dichtolemente 7 einfaoher and without much resistance possible, with one Einsehubweg or 45 are hlntertialb a arranged in the blind hole of the sealing element 7 or shoulder arranged shoulder , Depending on the strength and selected material of the latching arm 45, this can have elastic properties to a certain extent. Due to the small cross section of the Rastanns 45 this can form the desired coupling connection with the shoulder in the blind hole of the sealing element 7. As a result, a certain anchoring or latching of the locking arms 45 or 45 is achieved in the elastically deformable sealing element 7 in the return movement. Especially with siliconized surfaces of the sealing element 7, this embodiment of the latching arms 45 is advantageous instead of a mostly circumferentially formed locking cone. Thus, the shoulder and the pre-arranged in the distal direction passage opening can be formed with a smaller cross section, which serves only to receive the cross section of the coupling extension 41. The or moreover projecting latching arms 45 with the small cross-sectional width based on the entire circumference of the coupling extension 41 then penetrate due to the elastic deformation of the sealing element 7 and optionally a radial elastic deformation of the locking arms 45 in conjunction with an exemption in Kupplungsfört rate 41 in the blind hole.
    For coupling the coupling part 37 with the piston rod 17, elastically deformable coupling arms 46 may be provided on the base body 40 of the coupling part 37 on the side facing the piston rod 17, which can be detachably coupled to a coupling element 47 formed on the piston rod 17. In this case, the coupling arms 46 are preferably resilient in the radial direction and engage behind N2011 / 14400 lOlflC / OM 1 1ΛC1 Mr R374 p.niq / 038
    S. 14:50:28 * 12-05-2011 »« * · · · · »· * * · I Φ ·» · ** · * * * • * * * * · · »» · 20/38 - 16- the coupling member 47 on the piston rod 17 facing side. The dimensions and dimensions of the coupling arms 46 in the coupled position with the coupling element 47 are selected so that they have an outer dimension, which correspond approximately to the inner dimension of the syringe barrel 15. For a decoupling of the piston rod 17 is not possible until a certain cross-sectional widening takes place in order to effect the radial expansion of the coupling elements 46 and so perform the uncoupling process. Since the syringe cylinder 15 is usually formed of glass, it is advantageous if its inner wall over its entire length has almost the same cross-section or the same cross-sectional dimension.
    As can now better be seen from FIG. 1, here the ejection unit 25 is in its activated position, in which the coupling extension end 42 has pierced the bottom 39 of the piston stopper 16 and lies with its distal end against the proximal end of the base body 40 or is supported. In this Auspressstellung is the first locking element 43, which was previously arranged in the recess 44 of the piston stopper 16, according to the relative displacement on the inside of the bottom 39 of the blind hole 38 in the interspersed by the coupling extension 41 area. By this supporting effect of the bottom 39, an additional sealing effect on the proximal end face of the piston stopper in the contact area or passage area of the clutch continuation set 41 is created. This is because the bottom 39 has a relatively thin wall thickness and so the internal pressure occurring during the dispensing operation in this area leads to no leakage
    In Fig. 9, the retracted position and thus the protective position of the needle unit 12 within the syringe barrel 15 dargestelit. In this case, the piston rod 17 has already been separated from the Kuppiungsteil 37. In order to perform this retraction movement of the piston stopper 16 better, at least one further snap-action element 48 can additionally be arranged or formed on the coupling extension 41 between the base body 40 and the first latching element 43. This is due to the backward movement of the ejection unit 25 together with the needle unit 12 on a shoulder 49 formed in the blind hole 38 of the piston stopper 16. To form the shoulder 39, the blind hole can have sections with different cross sections 50, 51, wherein in the exemplary embodiment shown here the cross section 51 has a smaller cross sectional dimension than the cross section 50 in the region of the section facing the bottom 39. N201V14400
    No. · R374 P.020 / 038 25 * 4 4 4 • 1 * 51: 0 »« 12-05-2011 • · · · · * 9 4 4 ♦ · · «« * # »t» ··· • · · · • 9 4 9 4 4 »21/38 -17-
    As can now better be seen from a synopsis of FIGS. 9 and 10, as already described above, the syringe barrel 15, starting from its narrowed proximal end portion toward the distal end, has an almost identical cross-sectional dimension. At the distal end of Spritzenzyiinder 15 is further simplified yet a handling element 52 is shown, which is preferably part of the squeezing unit 25. This handling element 52 is preferably formed from two semi-bodies that can be joined together in the radial direction, which are held fixed in the axial direction by way of an extension 53 of the syringe assembly 15. For the mutual connection of the two half-bodies to form the handling element 52 may serve any known snap and / or locking elements.
    In order to carry out the uncoupling process described above between the coupling element 47 of the piston rod 17 and the coupling arms 46 of the coupling part 37, a light inside worlds 54 of a passage 55 in the handling element 52 in a distal portion is greater than an outer cross-sectional dimension of the coupling arms 46 in the undeformed Position. Thus, a radial expansion of the coupling arms 46 is made possible so as to be able to perform the uncoupling process.
    In order to achieve an axial positional fixation of the coupling part 47 relative to the syringe assembly 15 and thus to avoid renewed re-injection of the injection syringe 20, it is advantageous if between the Kupptungsteil 37, in particular of the base body 40, and the handling element 52 a hate device 56 with cooperating holding elements 57th , 58 is formed. In this embodiment shown here, the first holding member 57 is formed on the base part 40 of the coupling stiffener 37, for example in the form of a circumferential groove-shaped recess into which at least the further HaReelement 58 engages latching in the securing position. The further holding element 58 in the region of the handling element 52 may be formed radially resiliently or elastically deformable, which engages lockingly after sufficient return movement of the coupling part 37 in the designated first holding member 57. Depending on the design and type of the selected holding elements 57,58 to each other, an axial displacement of the remaining squeezing unit 25 and the needle unit 12 in at least one direction - prevented proximally and / or distally. Preferably, however, a further extraction of the remaining squeezing unit 25 together with the needle unit 12 can also be prevented.
    N2011 / 144QQ -ιο / η ^ / οηιι 14- ^ 9
    No. · R374 P.021 / 038 -18-
    S 14:51:53. 12-05-2011 22'38
    In order to prevent a renewed insertion of the piston rod 17 with its Kuppiungsefement 47 in the coupling part 37, in particular the base body 40 with the coupling arms 46, at least one guide element 59 may be arranged on the handling element 52 in the region of its distal end, which projects into the cross section of the passage channel 55 , The Leiteiement 59 may, for example, arcuate curved toward be formed in the direction of the longitudinal axis. Preferably, however, a plurality of guide elements 59 are provided so as to prevent the re-replacement of the piston rod 17 in the syringe 20.
    It is understood that the described embodiments are variously modified within the scope of the inventive concept, e.g. with regard to the arrangement of the guide knobs 1 relative to one another and / or relative to the [latching hook 8, with regard to the materials and the pitch angle of the guide tracks 10.
    In the previously described syringes 20 is a syringe type, in which the drug is already filled and provided for delivery. This is called a pre-filled syringe, especially glass syringe. The material of the syringe barrel 15 is selected from glass. The syringe internal space occupying the medicament is completely impervious to bacterial leakage at its proximal end by the sealing element 7 which is punctured up to activation and at its distal end by the still pierced piston stopper 16 against the inner wall of the syringe cylinder 7 only after activation of the injection syringe head 21 Twisting the cap tip 23 pierces the distal end of the cannula 3, the bottom of the sealing element 7 and thus provides the line connection with the interior of the syringe barrel 15 and the drug associated therewith. Then, the delivery of the stored medicament can take place.
    Furthermore, the unused position of the individual components relative to one another as the rest position or originality state and the position of the needle unit 12, at which a line connection with the interior of the syringe cylinder 15 has been produced, are referred to as the activation position. The same operating states or positions of the expressing unit 25 can also be designated with this information. If the needle unit 12 has been moved back into the syringe barrel 15, it is possible to speak of a disposal or protective position.
    For the sake of order, it should finally be pointed out that, for a better understanding of the structure of the injection syringe 20, in particular its injection syringe head 21, N2011 / 14400
    Nr. R374 P. 022/038 -19- · 14: 52: 3¾ »12-05-2011 23/38 25 • · * · · as well as their Auspreeeinheit 25, these or their components partly un-scaled and / or enlarged and / or reduced in size.
    The task underlying the independent inventive solutions can be seen from the description. All statements on ranges of values in the description of the present invention should be understood to include any and all sub-ranges thereof, e.g. Is the indication 1 to 10 to be understood that all sub-areas, starting from the lower limit 1 and the upper limit 10 are included, i. all subregions begin with a lower limit of 1 or greater and end at an upper limit of 10 or less, e.g. 1 to 1.7, or 3.2 to 8.1 or 5.5 to 10.
    The embodiments show possible embodiments of the syringe 20, in particular their injection syringe head 21 and the squeezing unit 25, it being noted at this point that the invention is not limited to the specifically illustrated embodiments thereof, but rather various combinations of the individual embodiments are possible with each other and this possibility of variation on the basis of the doctrine of technical action by objective invention lies in the ability of a professional working in this technical field. So there are also all conceivable ") variants, which are possible by combinations of individual details of the illustrated and described embodiment variant, includes the scope of protection. Furthermore, individual features or combinations of features from the different exemplary embodiments shown and described can also represent independent, inventive or inventive solutions.
    Above all, the individual in FIGS. 1, 2, 3; 4; 5; Figures 6 to 12 show the subject matter of independent solutions according to the invention. The relevant objects and solutions according to the invention can be found in the detailed descriptions of these figures. N2011 / 14400 io / ne; / onii 14- ^ 4
    No .: R374 P.023 / 038 28/38 J4: 55: 3S. 12-05-2011 9 · ♦ * *
    Reference symbol Positioning cam 36 Floor element Pinion 37 Coupling part Cannula 38 Blind hole Holder 39 Bottom Guide sleeve 40 Base body Coupling 41 Coupling extension Sealing element 42 Coupling extension latching hook 43 Locking element Window 44 Locking recess Sliding link 45 Rastann Sliding extension 46 Coupling arm Needle unit 47 Coupling element Bar 48 Locking element Protective cap 49 Shoulder Syringe cylinder 50 Cross section Piston stopper 51 Cross section Piston rod 52 Handling element Freeing 53 Extension Sealing washer 54 Clearance of injection syringe head 56 Holding device Protective cap base 57 Retaining cap Protective cap tip 58 Retaining element Breaking point 59 Guide element Pressing unit 60 Sealing ring Projection Recess Shank Approach Guide body Longitudinal rib Locking element Locking element Locking element Locking device N2011 / 14400 P.028 / 038 ιο / ηκ / Ίηΐΐ 14- ^ 7 No R3 74
    权利要求:
    Claims (18)
    [1]
    -1 - 5 44:53:16. 1. A syringe head (21) for an injection syringe (20) with a needle unit (12) arranged in a guide sleeve (5) and slidable therein, and a pinion (2) through which the needle unit (12) is movable axially relative to a syringe assembly (15) from an inoperative position to an activation position, characterized in that the pinion (2) has at least one guide nub (1) which is selectively connected to one of two in the guide sleeve (1). 5) provided link tracks (10) is engageable in engagement, wherein the link tracks (10) have opposing slopes.
    [2]
    2. hypodermic syringe head (21) according to claim 1, characterized in that the pinion (2) comprises two guide knobs (1), which are arranged in a perpendicular to a longitudinal axis aligned plane and circumferentially spaced from each other and for displacing the needle unit (12) from the rest position to the activation position only one of the two Fihrungnoppen (1) with one of the two slide tracks (10) is engageable in engagement.
    [3]
    3. hypodermic syringe head (21) according to claim 2, characterized in that in the FqhrungshQIse (5) in a peripheral region between the two slide tracks (10) an exemption (18) is formed and the release (18) for receiving that Fühngsnoppens (1) is used, which during the adjustment of the needle unit (12) with none of the slide tracks (10) is engaged.
    [4]
    4. Injection syringe head (21) according to one of Ansprüchel to 3, characterized in that the needle unit (12), in particular the cannula holder (4), and the guide sleeve (5) in the activation position by means of cooperating locking elements (33, 34) of a locking device ( 35) are held in the axial direction relative to each other. N2011 / 14400 1 o / flU / 9Π 1 1 1 A Rd Nr R374 P.024 / 038 * «14:53:51. 12-05-2011 25/38 • Φ * * ο # -2-
    [5]
    5. hypodermic syringe head (21) according to one of claims 1 to 4, characterized in that the needle unit (12), in particular the cannula holder (4), with the pinion (2) rotatable about the longitudinal axis, but locked in the axial direction is coupled.
    [6]
    6. Injection syringe head (21) according to one of claims 1 to 5, characterized in that the needle unit (12), in particular the cannula holder (4), in the guide sleeve (5) is guided in a straight line guided in the axial direction.
    [7]
    7. Injection syringe head (21) according to one of claims 1 to 6, characterized in that at the end of each slide track (10) a link extension (11) is provided, in soft the guide knobs (1) in the activation position of the needle unit (12) can be unlocked ,
    [8]
    8. Injection syringe head (21) according to one of claims 1 to 7, characterized in that the distal end of the guide sleeve (5) is designed as a coupling (6).
    [9]
    9. Irjektionsspritzenkopf (21) according to any one of claims 1 to 8, characterized in that on an outer side of the guide sleeve (5) at least one Längsrip-pe (31) is arranged, which against rotation on a latching member (32) of the injection syringe head (21 ) supporting protective cap (14) is supported.
    [10]
    10. Expressing unit (25) for a syringe (20) comprising a piston rod (17), a coupling part (37) with a base body (40) and on the side facing away from the piston rod (17) side protruding coupling extension (41) and a piston plug (16) with a starting from one of the piston rod (17) end facing in blind hole (38) which is closed with a bottom (39), wherein the coupling extension (41) projects into the blind hole (38) and in an unactuated Ausgansstellung the plunger stopper (16) in the axial direction of the base body (40) is arranged distanced and further the bottom (39) of the blind hole (38) from a Kupplungsfortsatzende (42) of the coupling extension (41) is durchurchstochen, characterized in that at the coupling extension ( 41) at least a first latching element (43) is angeordret which in the unactuated Ausgansstellung in one in the piston N2011 / 14400 1 o / mW 5> m 1 1 ά Nr R374 P.025 / 038 * 5 # · · * * * * * * * * * * * * * * * * * * * 44: 54: 3¾ * 12-05-2011 m · * ♦ »I · '* 26/38 -3- stuff (16 ) in the region of the blind hole (38) arranged latching recess (44) is inserted.
    [11]
    11. ejection unit (25) according to claim 10, characterized in that the first latching element (43) in adjacent position of the base body (40) and the piston stopper (16) at the bottom (39) of the blind hole (38) in the coupling of the extension ( 41) applied area abuts.
    [12]
    12. ejection unit (25) according to claim 10 or 11, characterized in that on the coupling extension (41) between the base body (40) and the first latching element (43) a further latching element (48) is arranged, which during the return movement of the ejection unit ( 25) on one in the blind hole (38) of the piston stopper (16) formed shoulder (49) is supported fitting.
    [13]
    13. ejection unit (25) according to any one of claims 10 to 12, characterized in that the coupling extension end (42) on the side facing away from the piston rod (17) side pfeHförmig is tapered and at least one, preferably two, the cross section of the coupling extension (41 ) comprises superior latching arms (45).
    [14]
    14. ejection unit (25) according to any one of claims 10 to 13, characterized in that the base body (40) of the coupling part (37) on the piston rod (17) facing side elastically deformable coupling arms (46), which with a on the Piston rod (17) formed coupling element (47) are detachably coupled Sind.
    [15]
    15. A squeezing unit (25) according to any one of claims 10 to 14, characterized in that it further comprises a handling element (52) soft with a distal end of a syringe barrel (15) can be coupled, and a clear inner width (54) of a Passage passage (55) in the handling element (52) is formed larger in a distal portion than an outer cross-sectional dimension of the coupling arms (46) in their undeformed position. N2011H4400 1 O / ns / 0f - 1 1 Δ RR No. · R374 P.026 / 038 44: 55: 0 · 12-05-2011 27/38 ZS

    -4-
    [16]
    16. ejection unit (25) according to any one of claims 10 to 15, characterized in that between the base body (40) of the Kupplungsteiis (37) and the Handha-bungseiement (52) a holding device (56) with zusammenwrkenden holding elements (57,56) is formed, which prevent at least one axial adjustment of the coupling part (37) in the proximal direction in engaging holding elements (57,58).
    [17]
    17. ejection unit (25) according to any one of claims 15 or 16, characterized in that the handling element (52} in the region of its distal end at least one guide element (58) is arranged, which projects into the cross section of the passage channel (55).
    [18]
    18. Injection syringe (20) comprising a syringe barrel (15), a syringe head (21) according to any one of claims 1 to 10 and a squeezing unit (25) according to any one of claims 11 to 17. Pharma Consult Ges.m.b.H. &Amp; Co Nfg KG by lawyers BurafflnTRirtner Rechtsanwalt GmbH 12/05/2011 14:56 Nr .: R374 P.027 / 038
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    同族专利:
    公开号 | 公开日
    EP2678054A1|2014-01-01|
    CN103492006A|2014-01-01|
    CA2831102A1|2012-08-30|
    JP2014515624A|2014-07-03|
    CA2831102C|2019-04-02|
    US20140052071A1|2014-02-20|
    AT511259A3|2012-12-15|
    EP2678054B1|2015-04-08|
    WO2012113008A1|2012-08-30|
    RU2013142914A|2015-03-27|
    US9289563B2|2016-03-22|
    引用文献:
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    AT404430B|1996-06-25|1998-11-25|Med Plastic Ag|INJECTION SYRINGE HEAD WITH ORIGINAL LOCK|
    EP1232763A1|2001-02-14|2002-08-21|Sergio Restelli|Disposable syringe|
    AT410897B|2002-01-09|2003-08-25|Pickhard Brigitte|INJECTION SYRINGE HEAD WITH ORIGINAL LOCK|
    US6613016B1|2003-01-21|2003-09-02|Jen Chuan Ku|Safety hypodermic syringe|
    AT502791B1|2006-04-06|2007-05-15|Pharma Consult Ges M B H & Co|Injection syringe, has plastic needle holder enclosing stainless steel injection needle, where holder receives injection solution in relation to interior of cylinder and is sealed off by sealing insert, by which rear end of needle protrudes|
    AT505616B1|2008-02-07|2009-03-15|Pickhard Brigitte|INJECTION sYRINGE|FR2991578B1|2012-06-06|2019-12-27|L'oreal|COMPOUNDS FOR ANTI-AGING AND DRY SKIN APPLICATION|
    DE102013007063A1|2013-04-19|2014-10-23|Kocher-Plastik Maschinenbau Gmbh|container|
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    RU2685684C2|2014-02-18|2019-04-22|Петер СКУФЦА|Delivery system for delivering medical or pharmaceutical compounds|
    DE102014008610A1|2014-06-06|2015-12-17|Kocher-Plastik Maschinenbau Gmbh|dispenser|
    AU2016235054B2|2015-03-24|2020-07-16|Kaleo, Inc.|Devices and methods for delivering a lyophilized medicament|
    CA2990950A1|2015-06-30|2017-01-05|Kaleo, Inc.|Auto-injectors for administration of a medicament within a prefilled syringe|
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    US10888693B2|2017-08-22|2021-01-12|Warsaw Orthopedic, Inc.|Drug pellet injector needle and method|
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    CN111374680B|2020-03-31|2020-10-02|江苏苏云医疗器材有限公司|Blood taking needle head protection device|
    法律状态:
    2016-05-15| REJ| Rejection|Effective date: 20160515 |
    优先权:
    申请号 | 申请日 | 专利标题
    AT1072011|2011-02-23|
    ATA680/2011A|AT511259A3|2011-02-23|2011-05-12|INJECTION SPRAY HEAD, SPRING UNIT, AND INJECTION SPREADING THEREFOR|ATA680/2011A| AT511259A3|2011-02-23|2011-05-12|INJECTION SPRAY HEAD, SPRING UNIT, AND INJECTION SPREADING THEREFOR|
    RU2013142914/14A| RU2013142914A|2011-02-23|2012-02-23|INJECTION SYRINGE WITH CYLINDER, HEAD OF THE INJECTION SYRINGE AND EXTENDING BLOCK|
    CA2831102A| CA2831102C|2011-02-23|2012-02-23|Syringe with syringe barrel, syringe head and ejector unit|
    JP2013554746A| JP2014515624A|2011-02-23|2012-02-23|Syringe head, extrusion unit, and syringe formed therefrom|
    PCT/AT2012/050024| WO2012113008A1|2011-02-23|2012-02-23|Syringe head, ejector unit, and syringe formed from same|
    EP12714924.3A| EP2678054B1|2011-02-23|2012-02-23|Head of an injection syringe, injection assembly and injection syringe|
    US14/000,927| US9289563B2|2011-02-23|2012-02-23|Syringe with syringe barrel, syringe head and ejector unit|
    CN201280010097.3A| CN103492006A|2011-02-23|2012-02-23|Syringe head, ejector unit, and syringe formed from same|
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